Last week, you analyzed bacterial growth on your plates using a SIR table. The following table was taken from an experiment published in the primary literature. Rather than raw data measurements, it indicates the number of plates that showed each result. Use this table to answer the questions on this page.

Antibiotic susceptibility results for Acinetobacter spp.

AntibioticSIRCeftazidime005Imipenem503Piperacillin-Tazobactam503Source: Bhattacharya, et al. (2015) A method for early detection of antibiotic resistance in positive blood cultures: Experience from an oncology centre in eastern India. Ind J Med Micro. 33(5):53-58.

Question 1

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Based on what you learned about using SIR tables, these three antibiotics have the following effects on the bacteria tested (Acinetobacter spp.):

• Choose...  Ceftazidime
• all strains somewhat resistant
• all strains resistant
• all strains susceptible
• mix of susceptible & resistant strains

 

• Choose... Imipenem
• all strains somewhat resistant
• all strains resistant
• all strains susceptible
• mix of susceptible & resistant strains
•  
• Choose...Piperacililn-Tazobactam
• all strains somewhat resistant
• all strains resistant
• all strains susceptible
• mix of susceptible & resistant strains

 

 

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Based on these results, if you know that an antibiotic that was NOT tested attacks bacteria with a mechanism that is similar to Ceftazidime, would it be a good choice to treat an Acinetobacter infection?

Select one:

a. No, it is highly likely that Actinetobacter would also be resistant to this antibiotic

b. Yes, it would be a good choice

c. Not the best choice, since some strains appear resistant

d. There is no way to generalize the experimental results to drugs that weren't tested

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