How do search for answers to the foDiscussion Part Two (graded)

He returns to your clinic for follow-up blood work, and 4 values catch your attention:

 AST 430 U/L ALT 535 U/L Bilirubin 41 mg/dl BG 60 mg/dl He admits to a history of moderate-to-high alcohol intake (>12 drinks/week for >10 years). He is slightly febrile (99.7°F) and has abdominal tenderness. He also admits to taking several, different over-the-counter pain relievers of different brands daily and continuously to combat the pain in his knee, in addition to his prescription(s) in Part One. You decide to run a toxicology lab, and it reveals a blood acetaminophen concentration of 58 µg/mL.

• What is the diagnosis at this point in his case? Please explain the mechanism for how this occurs/occurred, and the antidote's mechanism of action.
• What is the subsequent management and treatment for this individual related to the diagnosis in Part One.

Discussion Part Three (graded)

This is your third time seeing this patient, and he reports the NSAID that he has been prescribed is not addressing his pain. He reports hllowing question:

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