Question 11

Which of the following is NOT involved in transcriptional regulation ?

a) the TATA box.

b) enhancers.

 c) the poly-A signal.

 d) the regulatory promoter.

 e) the core promoter.

 

Question 12

Which of the following is NOT involved in transcriptional termination in eukaryotes (by RNA polymerase II) ?

a) involves cleavage of the pre-mRNA.

b) depends on a specific sequence of RNA.

c) depends on a protein, Rat.

d) phosphorylation of RNApol II by helicase

 e) involves exonuclease activity.

 

Question 13

The term "pre-mRNA" or "primary transcript" refers to ____________________.

a) prokaryotic mRNA.

b) genes at the DNA level, pre-transcription.

c) primary tranacripts are new eukaryotic transcriptin need of processing to become a fully mature mRNA.

d)  new, unprocessed RNA of eukaryotes.

 e) untranslated upstream regions of mRNA transcripts.

 

Question 15

The DNA sequence where RNA polymerase binds at the beginning of transcription is called the ____________________.

a) initiator.

b) operator.

c) The promoter is found at the beginning of a gene. RNA polymerase binds to this sequence and then moves along the DNA strand to synthesize the transcript.

d)  terminator.

 e) promoter.

 

Question 1

Enhancers, unlike regulatory promoters,

a) do not have to be in a specific location with respect to their regulated gene.

b) cannot be transcribed.

 c) do not have to contain specific DNA sequences

 d) show little sequence conservation across species

 e) are made of protein

 

Question 5

Which of the following would be a grossly unspecific way to regulate eukaryotic genes?

a) control of alternative splicing.

b) control of transcription

c) control of mRNA stability

 d) control of capping.

 e) control of degradation.

 

Question 7

The activity of an enzyme is LEAST likely to be controlled by which of the following?

a) translation.

b) RNA processing.

 c) post-translational covalent modification of the protein.

 d) changes to substrate concentration.

 e) transcription.

 

Question 9

An operon is__________

a) the coding sequence in the open reading frame of eukaryotic proteins.

b) a non-coding sequence that interrupts the open reading frame of proteins.

c) a DNA-binding protein

d) a set of genes transcribed as a single unit.

 

Question 10

Operons consist of all of the following EXCEPT_________

a) a promoter sequence.

b) a regulatory protein.

c) an operator sequence.

 d) two or more structural genes.

 

Question 11

Regulatory elements are________

a) genes that control the expression of other genes.

b) minerals that bind enzymes as cofactors, regulating their function.

c) structural genes that are regulated.

 d) sequences that help control transcription. 

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