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MCS,PHD
Argosy University/ Phoniex University/
Nov-2005 - Oct-2011
Professor
Phoniex University
Oct-2001 - Nov-2016
Treating psoriasis with the “Doctorfish of Kangal.” Refer to the Evidence-Based Research in Complementary and Alternative Medicine (Dec. 2006) study of treatingpsoriasis with ichthyotherapy, presented in Exercise 2.133 (p. 85). (Recall that the therapy is also known as the “Doctorfish of Kangal,” since it uses fish from the hot pools of Kangal, Turkey, to feed on skin scales.) In the study, 67 patients diagnosed with psoriasis underwent three weeks of ichthyotherapy. The Psoriasis Area Severity Index (PASI) of each patient was measured both before and after treatment. (The lower the PASI score, the better is the skin condition.) Before- and aftertreatment PASI scores were compared with the use of the Wilcoxon signed rank test.
a. Explain why the PASI scores should be analyzed with a test for paired differences.
b. Refer to the box plots shown in Exercise 2.133. Give a reason that the researchers opted to use a nonparametric test to compare the PASI scores.
c. The p -value for the Wilcoxon signed ranks test was reported as p
Exercise 2.133
Treating psoriasis with the “Doctor fish of Kangal” Psoriasis is a skin disorder with no known cure and no proven effective pharmacological treatment. An alternative treatment for psoriasis is ichthyotherapy also known as therapy with the “Doctor fish of Kangal.” Fish from the hot pools of Kangal, Turkey, feed on the skin scales of bathers, reportedly reducing the symptoms of psoriasis. In one study, 67 patients diagnosed with psoriasis underwent three weeks of ichthyotherapy. (Evidence-Based Research in Complementary and Alternative Medicine , Dec. 2006). The Psoriasis Area Severity Index (PASI) of each patient was measured both before and after treatment. (The lower the PASI score, the better is the skin condition.) Box plots of the PASI scores, both before (baseline) and after three weeks of ichthyotherapy treatment, are shown in the accompanying diagram
a. Find the approximate 25th percentile, the median, and the 75th percentile for the PASI scores before treatment.
b. Find the approximate 25th percentile, the median, and the 75th percentile for the PASI scores after treatment.
c. Comment on the effectiveness of ichthyotherapy in treating psoriasis.

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