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MCS,PHD
Argosy University/ Phoniex University/
Nov-2005 - Oct-2011
Professor
Phoniex University
Oct-2001 - Nov-2016
14.  ![]()
The level of monoamine oxidase (MAO) activity in blood platelets (nm/mg protein/hr) was determined for each individual in a sample of 43 chronic schiz- ophrenics, resulting in x = 2.69 and s1 = 2.30, as well as for 45 normal subjects, resulting in y = 6.35 and s2 = 4.03. Does this data strongly suggest that true average MAO activity for normal subjects is more than twice the activity level for schizophren- ics? Derive a test procedure and carry out the test
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using a = .01. [Hint: H0  and Ha  here have a differ- ent form from the three standard cases. Let m1 and m2  refer  to  true  average  MAO  activity  for  schizo- phrenics and normal subjects, respectively, and con- sider the parameter u = 2m1  - m2. Write H0  and Ha in terms of u, estimate u, and derive sˆ uˆ  (  Reduced Monoamine  Oxidase  Activity  in  Blood  Platelets from  Schizophrenic  Patients,   Nature,  July  28, 1972: 225—226).]
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