Maurice Tutor

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  • MCS,PHD
    Argosy University/ Phoniex University/
    Nov-2005 - Oct-2011

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    Phoniex University
    Oct-2001 - Nov-2016

Category > Management Posted 30 Nov 2017 My Price 7.00

Levenberg–Marquardt Method

Use the Levenberg–Marquardt Method with λ = 1 to fit the blood concentration model (4.21) to the data of Example 4.11 without linearization.

Example 4.11

Fit the model (4.21) with the measured level of the drug norfluoxetine in a patient’s bloodstream, given in the following table:

Solving the normal equations yields k ≈ 2.28 and c2 ≈ −0.215, and c1 ≈ e2.28 ≈ 9.77. The best version of the model is y = 9.77te−0.215t , plotted in Figure 4.9. From the model, the timing of the peak concentration and the half-life can be estimated.

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Maurice Tutor
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Status NEW Posted 30 Nov 2017 09:11 PM My Price 7.00

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