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MCS,PHD
Argosy University/ Phoniex University/
Nov-2005 - Oct-2011
Professor
Phoniex University
Oct-2001 - Nov-2016
A physiologist conducts an experiment designed to determine the effect of exogenous thyroxin (a hormone produced by the thyroid gland) on activity. Forty male rats are randomly assigned to four groups such that there are 10 rats per group. Each of the groups is in jested with a different amount of thyroxin. Group 1 gets no thyroxin and receives saline solution instead. Group 2 receives a small amount, group 3 a moderate amount, and group 4 a high amount of thyroxin. After the injections, each animal is tested in an open-field apparatus to measure its activity level. The open-field apparatus is composed of a fairly large platform with sides around it to prevent the animal from leaving the platform. A grid configuration is painted on the surface of the platform such that the entire surface is covered with squares. To measure activity, the experimenter merely counts the number of squares that the animal has crossed during a fixed period of time. In the present experiment, each rat is tested in the open-field apparatus for 10 minutes. The results are shown in the table; the scores are the number of squares crossed per minute.

a. What is the overall null hypothesis?
b. Using _ _ 0.05, what do you conclude?
c. What is the size of the effect, using vˆ2?
d. Evaluate the a priori hypothesis that a high amount of exogenous thyroxin produces an effect on activity different from that of saline. Use ?? = 0.052 tail.
e. Use the Tukey HSD test with ?? = 0.05 to compare all possible pairs of means. What do you conclude?
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