18. Generally speaking,
the
genes for
directly
detect environmental
signals
(for
example,
the
Lac
transcribed…
a. All the
time (constitutively)$
b. Only when the
genes they regulate
c. Only when the
genes they regulate
d. Only when the
signal they detect is
19. The
fastestway
activity
would
a. Mutate
the
gene
b. Turn off
transcription
c. Prevent
translation
d. Prevent
degradation
e. Allosteric inhibition to
be: negatively of
of
of
of its
its
the
the 20. A portion
of
the
has
the
sequence:
What’sthe
sequence
of
a. 5’ CAUCGAAU 3’$
b. 5’ CATCGAAT 3’
c. 5’ UAAGCUAC 3’
d. 5’ CUTCGUUA 3’
e. 5’ TAAGCTAC 3’
25. “Classic” hemophilia is
a
recessive
defect
gene that produces
a
People
that lack
allele for
this gene have
frequency
of
males
clotting
disorder
is
who does not
have
whose father did
have it,
the
disorder.
What are
the
odds that a. We don’t
say
b. 1/5000
c. 1/10,000
d. 50%$
e. 100% know the regulatory proteins that Repressor protein) are are
transcribed
are
not
transcribed
present
regulate an enzymatic gene
mRNA
protein
protein$ template
DNA
5’ATTCGATG 3’
the
resulting strand for a transcript mRNA? a
blood clotting
disorder
resulting
in
an
X-linked
protein
called “Coagulation Factor VIII”.
the
wild-type
a
blood clotting
disorder.
The
born with this
about 1/5000 worldwide.
A
woman
the
disorder,
but
marries
a
man who does not
have
They have a
son.
their son has
the
disorder? genotype of the mother, so we can’t 29. Achromotopsia
is
a
heritable
autosomal
recessive
disorder
due to
a
defect in
the
ACMH3
gene.
Homozygotes
defective
in
this gene causes
are
completely color blind, get
early
cataracts,
and have a
varietyof
other sight disorders.
On
the
island of
Pinglap,
a
large fraction
of
the
population carries
this allele, and 4-10% of
the
population is
blind from infancy
.
This is
thought
to
be
due to
the
drastic
reduction
in
population size after a
hurricane
only 20
people
survived.
Prior to
this hurricane,
the
frequency
of
people
with achromotopsia
was similarto
that in
the
rest of
Indonesia:
1/84,000
peopledevelop
the
disorder.
The high incidence
of
this
disorder
on
this island is
an
example
of: a. Natural
selection
b. Induced
mutagenesis
c. Acclimation
d. Adaptation
e. The effects of
an
evolutionary bottleneck

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